E-ISSN 2756-4843 | ISSN 0794-5698
 
2020, Vol: 28, Issue: 1
28 / 1Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Research 


Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria

OLIVIA SOCHI EGBULE, Erkison Ewomazino Odih.

Abstract
Abstract
This study was conducted to detect the prevalence of metallo-beta-lactamases (MBLs) and extended-spectrum beta-lactamases (ESBLs) in bacterial isolates from clinical and community settings in Delta State, Nigeria. Eighty four isolates obtained from blood, urine wound and stool of patients and community subjects were analyzed and identified by standard microbiological methods. Carbapenemase detection was carried out using modified Hodge test. EDTA-disc synergy test was used to detect MBL production. ESBLs production was determined by double disc synergy test (DDST). ESBL production was detected in 36.7% isolates of Escherichia coli, 37.5% of Pseudomonas aeruginosaand 75% of Klebsiellapneumoniae. Co-production of MBL and ESBL was observed in 31.82% of the isolates. The study observed 2 major troubling findings. The first is the prevalence and co-production of MBLs and ESBLs both in hospitalized patients and in isolates of healthy community children. Second, antibiotic resistance is no longer only associated with selective pressure but may stably persist in bacteria. There is therefore the need for antibiotic alternative research.

Key words: Keywords: Antibiotic resistance, Multidrug resistance, Healthy children, Beta-lactamases, Plasmids


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by OLIVIA SOCHI EGBULE
Articles by Erkison Ewomazino Odih
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

EGBULE OS, Odih EE. Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria. Nig. J. Basic Appl. Sci.. 2020; 28(1): 7-14. doi:10.4314/njbas.v28i1.2

Web Style

EGBULE OS, Odih EE. Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria. http://www.njbas-udus.com/?mno=232166 [Access: November 08, 2020]. doi:10.4314/njbas.v28i1.2

AMA (American Medical Association) Style

EGBULE OS, Odih EE. Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria. Nig. J. Basic Appl. Sci.. 2020; 28(1): 7-14. doi:10.4314/njbas.v28i1.2


Vancouver/ICMJE Style

EGBULE OS, Odih EE. Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria. Nig. J. Basic Appl. Sci.. (2020), [cited November 08, 2020]; 28(1): 7-14. doi:10.4314/njbas.v28i1.2


Harvard Style

EGBULE, O. S. & Odih, . E. E. (2020) Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria. Nig. J. Basic Appl. Sci., 28 (1), 7-14. doi:10.4314/njbas.v28i1.2


Turabian Style

EGBULE, OLIVIA SOCHI, and Erkison Ewomazino Odih. 2020. Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria. Nigerian Journal of Basic and Applied Sciences, 28 (1), 7-14. doi:10.4314/njbas.v28i1.2


Chicago Style

EGBULE, OLIVIA SOCHI, and Erkison Ewomazino Odih. "Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria." Nigerian Journal of Basic and Applied Sciences 28 (2020), 7-14. doi:10.4314/njbas.v28i1.2


MLA (The Modern Language Association) Style

EGBULE, OLIVIA SOCHI, and Erkison Ewomazino Odih. "Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria." Nigerian Journal of Basic and Applied Sciences 28.1 (2020), 7-14. Print. doi:10.4314/njbas.v28i1.2


APA (American Psychological Association) Style

EGBULE, O. S. & Odih, . E. E. (2020) Prevalence of Extended-Spectrum Beta-Lactamases (ESBLs) and Metallo-BetaLactamases (MBLs) Among Healthy and Hospitalized Children in Abraka and Eku Communities, Delta State, Nigeria. Nigerian Journal of Basic and Applied Sciences, 28 (1), 7-14. doi:10.4314/njbas.v28i1.2




Most Viewed Articles
  • Isolation and Identification of Fungi Associated with the Spoilage of Sweet Orange (Citrus Sinensis) Fruits In Sokoto State
    I.Y. Tafinta, K.Shehu, H. Abdulganiyyu, A.M. Rabe and A. Usman
    Nig. J. Basic Appl. Sci.. 2013; 21(3): 193-196
    » Abstract & References

  • Heavy Metals and Physicochemical Properties of Soils in Kano Urban Agricultural Lands
    U.M. Dawaki, A.U. Dikko, S.S. Noma and U. Aliyu
    Nig. J. Basic Appl. Sci.. 2013; 21(3): 239-246
    » Abstract & References

  • Study on Biochemical Indices of Liver Function Tests of Albino Rats Supplemented with Three Sources of Vegetable Oils [English]
    K.E. Imafidon and L.O. Okunrobo
    Nig. J. Basic Appl. Sci.. 2012; 20(2): 105-110
    » Abstract

  • Effect of Sources of Organic Manure on Growth and Yields of Okra (Abelmoschus esculentus L.) in Sokoto, Nigeria [English]
    R.A. Tiamiyu, H.G. Ahmed and A.S. Muhammad
    Nig. J. Basic Appl. Sci.. 2012; 20(3): 213-216
    » Abstract

  • Optimum Temperature and Thermal Stability of Crude Polyphenol Oxidase from some Common Fruits
    AB Bello, MS Sule
    Nig. J. Basic Appl. Sci.. 2012; 20(1): 27-31
    » Abstract

    • Most Downloaded
  • Isolation and Identification of Fungi Associated with the Spoilage of Sweet Orange (Citrus Sinensis) Fruits In Sokoto State
    I.Y. Tafinta, K.Shehu, H. Abdulganiyyu, A.M. Rabe and A. Usman
    Nig. J. Basic Appl. Sci.. 2013; 21(3): 193-196
    » Abstract & References

  • Optimization of Steam Distillation of Essential Oil of Eucalyptus tereticornis by Response Surface Methodology [English]
    M.S. Galadima, A.S. Ahmed, A.S. Olawale and I. M. Bugaje
    Nig. J. Basic Appl. Sci.. 2012; 20(4): 368-372
    » Abstract

  • The Swelling Behaviour of Polystyrene (PS)/ Polyvinylacetate (Pvac) Blends in Different Solvents and the Effects of -Cellulose used as Filler on the Electrical Conductivity. [English]
    P. A. P. Mamza and B.T. Nwufo
    Nig. J. Basic Appl. Sci.. 2008; 16(2): 165 -
    » Abstract

  • Biogas production through Co-digestion of palm oil mill effluent with cow manure
    Umar Hayatu Sidik, Firdausi Bin Razali, Sharifah Rafidah Wan Alwi, Fadimtu Maigari
    Nig. J. Basic Appl. Sci.. 2013; 21(1): 79-84
    » Abstract

  • Characterization and Classification of Soils on an Agricultural landscape in Dingyadi District, Sokoto State, Nigeria
    M.B. Sharu, M. Yakubu, S.S. Noma and A.I.Tsafe
    Nig. J. Basic Appl. Sci.. 2013; 21(2): 137 -147
    » Abstract

    • Most Cited Articles
    This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.
    The articles in Nigerian Journal of Basic and Applied Sciences are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
    Copyright © 2020 Nigerian Journal of Basic and Applied Sciences All Rights Reserved. Subject to change without notice from or liability to Nigerian Journal of Basic and Applied Sciences.
    For best results, please use Internet Explorer or Google Chrome

    Contact Information


    Nigerian Journal of Basic and Applied Sciences (NJBAS)

    Usmanu Danfodiyo University, Sokoto

    P.M.B. 2346, Sokoto, Nigeria

    email: njbas@udusok.edu.ng; publicationeditor.njbas@udusok.edu.ng 

    Mobile contact:+2348057937555

     

     
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use