E-ISSN 0331-8753 | ISSN 0794-5698
 

Original Research 


Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats

O. A. Sodipo, J. Yakubu, A. M. Dungus and B. Wampana.

Abstract
The research was conducted to investigate the phytochemical constituents, acute toxicity, the anti-inflammatory and antinociceptive activities of the ethanol extract of Balanites aegyptiaca (EEBA) leaves. The anti-inflammatory and antinociceptive activities at doses of 200, 400 and 600 mg/kg i.p were evaluated using hot plate and tail immersion methods (models) in albino rats. EEBA produced significant (p <0.05) and dose dependent anti-inflammatory and antinociceptive activities at all test doses (200, 400 and 600 mg/kg). Phytochemical constituents present in EEBA were found to be flavonoids, carbohydrates, saponins and glycosides which might be responsible for the established anti-inflammatory and antinociceptive activities in the plant extract. The leaf extract of the plant was found to be non-toxic with an intraperitoneal acute toxicity (LD50) of 2254 mg/kg.

Key words: Phytochemical, anti-inflammatory, antinociceptive, Balanites aegyptiaca


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by O. A. Sodipo
Articles by J. Yakubu
Articles by A. M. Dungus and B. Wampana
on Google
on Google Scholar
Article Statistics
 Viewed: 1467
Downloaded: 1


How to Cite this Article
Pubmed Style

Sodipo OA, Yakubu J, . Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats. Nig. J. Basic Appl. Sci.. 2019; 27(2): 39-46. doi:10.4314/njbas.v27i2.6


Web Style

Sodipo OA, Yakubu J, . Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats. http://www.njbas-udus.com/?mno=30119 [Access: March 28, 2020]. doi:10.4314/njbas.v27i2.6


AMA (American Medical Association) Style

Sodipo OA, Yakubu J, . Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats. Nig. J. Basic Appl. Sci.. 2019; 27(2): 39-46. doi:10.4314/njbas.v27i2.6



Vancouver/ICMJE Style

Sodipo OA, Yakubu J, . Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats. Nig. J. Basic Appl. Sci.. (2019), [cited March 28, 2020]; 27(2): 39-46. doi:10.4314/njbas.v27i2.6



Harvard Style

Sodipo, O. A., Yakubu, . J. & (2019) Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats. Nig. J. Basic Appl. Sci., 27 (2), 39-46. doi:10.4314/njbas.v27i2.6



Turabian Style

Sodipo, O. A., J. Yakubu, and A. M. Dungus and B. Wampana. 2019. Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats. Nigerian Journal of Basic and Applied Sciences, 27 (2), 39-46. doi:10.4314/njbas.v27i2.6



Chicago Style

Sodipo, O. A., J. Yakubu, and A. M. Dungus and B. Wampana. "Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats." Nigerian Journal of Basic and Applied Sciences 27 (2019), 39-46. doi:10.4314/njbas.v27i2.6



MLA (The Modern Language Association) Style

Sodipo, O. A., J. Yakubu, and A. M. Dungus and B. Wampana. "Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats." Nigerian Journal of Basic and Applied Sciences 27.2 (2019), 39-46. Print. doi:10.4314/njbas.v27i2.6



APA (American Psychological Association) Style

Sodipo, O. A., Yakubu, . J. & (2019) Antinociceptive Effect of the Ethanol Leaf Extract of Balanites aegyptiaca Linn in Albino Rats. Nigerian Journal of Basic and Applied Sciences, 27 (2), 39-46. doi:10.4314/njbas.v27i2.6





Most Viewed Articles
  • Isolation and Identification of Fungi Associated with the Spoilage of Sweet Orange (Citrus Sinensis) Fruits In Sokoto State
    I.Y. Tafinta, K.Shehu, H. Abdulganiyyu, A.M. Rabe and A. Usman
    Nig. J. Basic Appl. Sci.. 2013; 21(3): 193-196
    » Abstract & References

  • Heavy Metals and Physicochemical Properties of Soils in Kano Urban Agricultural Lands
    U.M. Dawaki, A.U. Dikko, S.S. Noma and U. Aliyu
    Nig. J. Basic Appl. Sci.. 2013; 21(3): 239-246
    » Abstract & References

  • Study on Biochemical Indices of Liver Function Tests of Albino Rats Supplemented with Three Sources of Vegetable Oils [English]
    K.E. Imafidon and L.O. Okunrobo
    Nig. J. Basic Appl. Sci.. 2012; 20(2): 105-110
    » Abstract

  • Effect of Sources of Organic Manure on Growth and Yields of Okra (Abelmoschus esculentus L.) in Sokoto, Nigeria [English]
    R.A. Tiamiyu, H.G. Ahmed and A.S. Muhammad
    Nig. J. Basic Appl. Sci.. 2012; 20(3): 213-216
    » Abstract

  • Optimum Temperature and Thermal Stability of Crude Polyphenol Oxidase from some Common Fruits
    AB Bello, MS Sule
    Nig. J. Basic Appl. Sci.. 2012; 20(1): 27-31
    » Abstract

  • Most Downloaded
  • Isolation and Identification of Fungi Associated with the Spoilage of Sweet Orange (Citrus Sinensis) Fruits In Sokoto State
    I.Y. Tafinta, K.Shehu, H. Abdulganiyyu, A.M. Rabe and A. Usman
    Nig. J. Basic Appl. Sci.. 2013; 21(3): 193-196
    » Abstract & References

  • Optimization of Steam Distillation of Essential Oil of Eucalyptus tereticornis by Response Surface Methodology [English]
    M.S. Galadima, A.S. Ahmed, A.S. Olawale and I. M. Bugaje
    Nig. J. Basic Appl. Sci.. 2012; 20(4): 368-372
    » Abstract

  • Biogas production through Co-digestion of palm oil mill effluent with cow manure
    Umar Hayatu Sidik, Firdausi Bin Razali, Sharifah Rafidah Wan Alwi, Fadimtu Maigari
    Nig. J. Basic Appl. Sci.. 2013; 21(1): 79-84
    » Abstract

  • The Swelling Behaviour of Polystyrene (PS)/ Polyvinylacetate (Pvac) Blends in Different Solvents and the Effects of -Cellulose used as Filler on the Electrical Conductivity. [English]
    P. A. P. Mamza and B.T. Nwufo
    Nig. J. Basic Appl. Sci.. 2008; 16(2): 165 -
    » Abstract

  • Characterization and Classification of Soils on an Agricultural landscape in Dingyadi District, Sokoto State, Nigeria
    M.B. Sharu, M. Yakubu, S.S. Noma and A.I.Tsafe
    Nig. J. Basic Appl. Sci.. 2013; 21(2): 137 -147
    » Abstract

  • Most Cited Articles