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Original Research 


Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae)

A. J. Yusuf, M. I. Abdullahi, A. M. Musa, A. K. Haruna, V. Mzozoyana and A. Sanusi.

Abstract
Purpose: Neocarya macrophylla has a wide range of medicinal uses in traditional medicine. The aim of the study was to isolate and characterize compound(s) from the stem bark of the plant.
Methods: (-)-Epicatechin (a flavan-3-ol) was isolated from the ethylaceate soluble fraction of the methanol stem bark extract of Neocarya macrophylla using a combination of silica gel and sephadex LH-20 column chromatography.
Results: The structure of the compound as (-)-epicatechin was confirmed on the basis of chemical test, 1D- & 2D-NMR spectroscopy and comparison with existing data in the literature.
Conclusion: This is the first report of isolation of epicatechin from the stem bark of the plant.

Key words: Neocarya macrophylla, stem bark, (-)-epicatechin, NMR analysis


 
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How to Cite this Article
Pubmed Style

Yusuf AJ, Abdullahi MI, Musa AM, Haruna AK, Sanusi VMaA. Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae). Nig. J. Basic Appl. Sci.. 2019; 27(2): 101-107. doi:10.4314/njbas.v27i2.14

Web Style

Yusuf AJ, Abdullahi MI, Musa AM, Haruna AK, Sanusi VMaA. Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae). http://www.njbas-udus.com/?mno=43246 [Access: March 29, 2020]. doi:10.4314/njbas.v27i2.14

AMA (American Medical Association) Style

Yusuf AJ, Abdullahi MI, Musa AM, Haruna AK, Sanusi VMaA. Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae). Nig. J. Basic Appl. Sci.. 2019; 27(2): 101-107. doi:10.4314/njbas.v27i2.14


Vancouver/ICMJE Style

Yusuf AJ, Abdullahi MI, Musa AM, Haruna AK, Sanusi VMaA. Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae). Nig. J. Basic Appl. Sci.. (2019), [cited March 29, 2020]; 27(2): 101-107. doi:10.4314/njbas.v27i2.14


Harvard Style

Yusuf, A. J., Abdullahi, . M. I., Musa, . A. M., Haruna, . A. K. & Sanusi, . V. M. a. A. (2019) Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae). Nig. J. Basic Appl. Sci., 27 (2), 101-107. doi:10.4314/njbas.v27i2.14


Turabian Style

Yusuf, A. J., M. I. Abdullahi, A. M. Musa, A. K. Haruna, and V. Mzozoyana and A. Sanusi. 2019. Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae). Nigerian Journal of Basic and Applied Sciences, 27 (2), 101-107. doi:10.4314/njbas.v27i2.14


Chicago Style

Yusuf, A. J., M. I. Abdullahi, A. M. Musa, A. K. Haruna, and V. Mzozoyana and A. Sanusi. "Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae)." Nigerian Journal of Basic and Applied Sciences 27 (2019), 101-107. doi:10.4314/njbas.v27i2.14


MLA (The Modern Language Association) Style

Yusuf, A. J., M. I. Abdullahi, A. M. Musa, A. K. Haruna, and V. Mzozoyana and A. Sanusi. "Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae)." Nigerian Journal of Basic and Applied Sciences 27.2 (2019), 101-107. Print. doi:10.4314/njbas.v27i2.14


APA (American Psychological Association) Style

Yusuf, A. J., Abdullahi, . M. I., Musa, . A. M., Haruna, . A. K. & Sanusi, . V. M. a. A. (2019) Isolation of Epicatechin from the Stem Bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae). Nigerian Journal of Basic and Applied Sciences, 27 (2), 101-107. doi:10.4314/njbas.v27i2.14




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